Medicine

Progressing ASO therapies coming from progression to application

.Competing rate of interests.R.S., M.S., H.G. and A.A.R. are actually coordinators of the 1M1M campaign. H.G. and also A.A.R. are panel of supervisors participants as well as R.S., M.S. and A.A.R. are actually members of the clinical advising board of N1C. A.A.R. makes known job by LUMC, which has licenses on exon-skipping innovation, several of which has actually been licensed to BioMarin as well as ultimately sublicensed to Sarepta. As co-inventor of several of these patents, A.A.R. was actually allowed to an allotment of royalties. A.A.R. even more reveals serving as ad hoc specialist for PTC Therapeutics, Sarepta Rehabs, Regenxbio, Dyne Therapies, Lilly, BioMarin Pharmaceuticals Inc., Eisai, Entrada, Takeda, Splicesense, Galapagos, Sapreme, Italfarmaco and Astra Zeneca. Previously 5 years, A.A.R. also carried out seeking advice from for Alpha Anomeric. A.A.R. also states subscription of the clinical advisory boards of Eisai, Hybridize Rehabs, Silence Rehabs, Sarepta Therapies, Sapreme as well as Mitorx. Over the last 5 years, A.A.R. was actually additionally a medical board of advisers member for ProQR. Pay for A.A.R. u00e2 s consulting and also advising activities is actually paid to LUMC. Previously 5 years, LUMC likewise received audio speaker gratuity coming from PTC Therapeutics, Alnylam Netherlands, Italfarmaco and also Pfizer and also cashing for contract analysis from Sapreme, Eisai, Galapagos, Synaffix and Alpha Anomeric. Job backing is obtained from Sarepta Rehabs as well as Entrada through unregulated gives. H.G. has absolutely nothing to make known in connection with the subjects covered in this particular manuscript. In the past 5 years, he has actually likewise acquired consultancy honoraria coming from UCB. M.S. obtained consultancy gratuity from Ionis, UCB, Prevail, Orphazyme, Biogen, Servier, Reata, GenOrph, AviadoBio, Biohaven, Zevra, Lilly and also Solaxa in the past 5 years, all unconnected to the present composition. R.S. possesses absolutely nothing to reveal in connection with the subjects covered within this document. She has received speaker and/or working as a consultant honoraria or sponsoring additions coming from Abbvie, Bial, STADA as well as Everpharma previously 5 years.

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